The second named storm of the year, caused by a "weather bomb" of low pressure in the Atlantic, will bring gusts of between 50mph (80kph) and 70mph (113kph).
Storm Brian will batter the UK.
Met Eireann has issued a Status Orange warnings and three Status Yellow warnings due to the incoming storm, and the southern half of the country is now bracing itself again for yet more high winds, and potential torrential rainfall.
Chief Forecaster Dan Suri said: 'Storm Brian is expected to bring strong south or southwesterly winds to much of Wales and southern and western England from early Saturday.
A dramatic live stream from Portcawl Lifeboats showed waves crashing over the pier this morning as the strong winds begin to take hold in the southern parts of Wales.
'We are more concerned about flooding occurring in areas such as the north western and south western parts of England and also Wales, which is why our 45 flood alerts and six flood warnings remain in place.
Ahead of the storm, a yellow warning for heavy rain has been issued for Northern Ireland. Weatherquest forecaster Adam Dury said: "The weather bomb actually happened on Thursday night but we won't see the stormy conditions until the early hours of Saturday". The Environment Agency's Alison Baptiste has warned the public to stay safe along the coast where there is set to be strong winds, large waves and some over-topping of coastal defences.
Now no flood alerts or flood warnings have been issued for the Anglian region by the Environment Agency (EA), but EA national flood duty manager, Alison Baptiste, said: "We urge people to stay safe along the coast".
The Met Office has also warned of the possibility of power loss.
A spokesman said: 'Fallen trees and other debris may temporarily block railway lines and damage overhead wires.
Wind speeds of up to 80mph in isolated areas has been predicted as the storm sweeps over the south of the United Kingdom and Ireland before moving northwards.