72 major genetic risk factors for breast cancer identified in new study

Plant-based diet converts breast cancer in mice from lethal to treatable form

More women at risk due to discovery of further cancer causing gene mutations

Breast cancer is the second most common cancer among women in the US, affecting one in every eight women.

'As well as identifying new genetic variants, we have also confirmed many that we had previously suspected.

With what the medical community already knows about BRCA1, BRCA2, other variants, plus the newly identified genes, it's estimated that about 39 percent of heritable ER-positive breast cancer risk can be explained, researchers said.

A further seven genes were identified specifically in association with breast cancers that lacked oestrogen receptors, which don't tend to respond to hormone based therapies.

Professor Doug Easton from the Centre for Cancer Genetic Epidemiology and a Fellow at Homerton College, the University of Cambridge - one of the lead investigators on the study - says: "These findings add significantly to our understanding of the inherited basis of breast cancer".

The optimal amount of physical activity is hard to define, but I would suggest at least doing 30 minutes of exercise five days a week to decrease the risk of breast cancer development in the general population. These new genetic variations, we will probably answer, " stresses Dr. Jocelyne Chiquette, clinician at the Centre for breast diseases at Quebec, which is one of the authors of the study.

U.S. co-author Professor Peter Kraft, from the Harvard TH Chan School of Public Health, said the findings revealed a wealth of new information about the genetic mechanisms underlying the disease.


Shirts are $20 each and proceeds will benefit local breast cancer awareness and support groups. "There's been a lot of research trying to figure out what that something else is. If a test is developed and a woman finds out she is at high risk, what steps are in place for her to take action in reducing that risk?" she told The New Daily.

Among breast cancer sufferers, those who rely on herbs, homeopathy or energy crystals to beat their disease are 5.68 times more at risk of an early death, a study found.

By analysing the 180 regions of the genome where are located some of the variations that predispose to breast cancer, it will be possible to determine the risk of a woman developing this cancer.

"I had genetic testing and I was negative for all the genetic testing", Moeller said.

Cancer patients who opt for alternative medicines over conventional treatment are two-and-a-half times more likely to die within five years of diagnosis, research revealed in August.

Lifestyle changes such as diet, body weight, exercise and alcohol consumption are some of the modifiable risk factors for this disease.

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